2012年11月4日日曜日

メモ: AHA2012

AHA2012
http://my.americanheart.org/professional/Sessions/ScientificSessions/Scientific-Sessions_UCM_316900_SubHomePage.jsp



解説 http://www.theheart.org/article/1464751.do 

一部訳

Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease (FREEDOM) : http://www.clinicaltrials.gov/ct2/show/NCT00086450
:糖尿病患者の、PCI と CABG 比較

  FREEDOM: CABG superior to PCI in diabetic patients with coronary disease
NOVEMBER 4, 2012
http://www.theheart.org/article/1469059.do
 FREEDOM : 糖尿病・多枝冠動脈病変では、冠動脈手術のほうがPCIより優れる H24/11/05 http://kaigyoi.blogspot.jp/2012/11/freedom.html


Trial to Assess Chelation Therapy (TACT) : http://www.clinicaltrials.gov/ct2/show/NCT00044213?term=TACT+chelation&rank=1
:キレート治療


【ω-3、ビタミン類】
Fish Oil Research with Omega-3 for Atrial Fibrillation Recurrence Delay [FORWARD] :http://clinicaltrials.gov/ct2/show/NCT00597220
Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation [OPERA] : http://clinicaltrials.gov/ct2/show/NCT00970489
:ω-3脂肪酸と心房細動

Physicians Health Study II (PHS II) :http://clinicaltrials.gov/show/NCT00270647 : マルチビタミンのCVD予防

Use of a Multidrug Pill in Reducing Cardiovascular Events (UMPIRE) : polypill(aspirin, simvastatin, atenolol, and lisinopril or hydrochlorothiazide)による心筋梗塞・卒中既往患者への投与効果

Trial for Efficacy of Capre on Hypertriglyceridemia (TRIFECTA) : http://clinicaltrials.gov/ct2/show/NCT01455844 : ω3と高TG血症

dal-OUTCOMES ; http://www.clinicaltrials.gov/ct2/show/NCT00658515?term=NCT00658515&rank=1 : 新規cholesteryl ester transfer protein (CETP) 阻害剤 dalcetrapibのrecent ACS患者への投与・・・効果不充分で早期中止となったトライアル


PCSK9阻害 : Anti-PCSK9抗体:LDL治療薬 phase I
http://kaigyoi.blogspot.jp/2012/03/anti-pcsk9phase-i.html



【幹細胞・左室機能障害】
Stem Cells in Patients with Ischemic Cardiomyopathy (SCIPIO) : 

Multicenter Automatic Defibrillator Implantation Trial—Reduce Inappropriate Therapy (MADIT RIT)  : high-rate cutoff and/or long delay to reduce inappropriate implantable cardioverter-defibrillator (ICD) or defibrillator-cardiac resynchronization therapy (CRT-D) responses, compared with standard programming.


RELAX-AHF : RLX030 (serelaxin) 急性心不全への応用

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